Daryl Murphy and Ciaran Clark have been called up on international duty.
Martin O’Neill has named an initial 33 man squad for the World Cup qualifiers against Georgia and Moldova in early October..
Ireland host Georgia on Thursday 6 October before travelling to take on Moldova on Sunday 9 October.
The Newcastle pair are two of seventeen players called up from Championship clubs, making up just over half of the Ireland squad.
Republic of Ireland Squad
Goalkeepers: Darren Randolph (West Ham United), Keiren Westwood (Sheffield Wednesday), Danny Rogers (Falkirk)
Defenders: Seamus Coleman (Everton), Cyrus Christie, Richard Keogh, Alex Pearce (Derby County) Paul McShane (Reading), John O’Shea (Sunderland), Shane Duffy (Brighton & Hove Albion), Ciaran Clark (Newcastle United), Marc Wilson (Bournemouth), Stephen Ward (Burnley)
Midfielders: Aiden McGeady (Preston North End), James McClean (West Bromwich Albion), Glenn Whelan (Stoke City), James McCarthy (Everton), Jeff Hendrick (Burnley), Stephen Quinn (Reading), David Meyler (Hull City), Conor Hourihane (Barnsley), Harry Arter (Bournemouth), Eunan O’Kane (Leeds United), Stephen Gleeson (Birmingham City), Callum O’Dowda (Bristol City), Robbie Brady, Wes Hoolahan (Norwich City), Anthony Pilkington (Cardiff City), Jonathan Hayes (Aberdeen)
Forwards: Shane Long (Southampton), Daryl Murphy (Newcastle United), Jonathan Walters (Stoke City), Kevin Doyle (Colorado Rapids)